After being rejected by three major journals, an RCT completed by 4,862 participants has been published in the Annals of Internal Medicine. The volunteers were adults spending more than 3 hours per day outside the home without occupational mask use. All were instructed to follow social-distancing and other public health measures, and those in the mask group were instructed to wear a mask when outside the home during the next month.
Infection with SARS-CoV-2 within one month occurred in 42 participants who were recommended to wear masks (1.8%) and 53 control participants (2.1%). The difference of 0.3% was not statistically significant (p = 0.38). Ordinarily, this would be described as a negative study.
“This should put an end to any Governor claiming that mask mandates are backed by science and data, but it won’t,” writes Kevin Roche of Roche Consulting.
“It should not be used as evidence to not wear a mask,” writes Leah Rosenbaum in Forbes.
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